FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam

Which method is known for forming emulsions with synthetic emulsifying agents?

1. Wet gum method

2. Dry gum method

3. Beaker method

4. Bottle method

The correct answer is: Beaker method

The beaker method is recognized for forming emulsions using synthetic emulsifying agents. This method allows for better control and visibility during the emulsification process. Using a beaker, the emulsifying agent can be gradually integrated into the aqueous phase, allowing for thorough mixing and stabilization of the emulsion. The versatility of the beaker method makes it particularly suitable for synthetic emulsifiers, which often require specific conditions to effectively reduce the interfacial tension between the oil and water phases. In contrast, the wet gum and dry gum methods typically involve natural emulsifying agents and have specific protocols that better suit those agents. The wet gum method uses a gum mixed with water before adding oil, while the dry gum method incorporates the oil first and then adds water. These methods are less adaptable to synthetic emulsifiers because they rely on the properties and behaviors of natural gums. The bottle method is similarly less optimal, as it usually involves shaking ingredients in a bottle, which may not achieve the fine dispersion needed for effective emulsion formation with synthetic agents. Thus, the beaker method stands out for its efficiency and compatibility with synthetic emulsifying agents.